NCT05746988

Carrageenan for the Prevention of Oral HPV Infection

Carrageenan for the Prevention of Oral HPV Infection: a Feasibility, Randomized Clinical Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: McGill University · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This is a placebo-controlled, triple-blind randomized clinical trial (RCT) designed to evaluate the feasibility of conducting a larger multicentric RCT investigating the effect of a Carrageenan mouthwash on oral HPV infection. Eligible participants will complete a single in-person visit at baseline, filling out a questionnaire on their electronic device and giving an oral rinse sample for HPV testing. They will receive an adequate supply of mouthwash and instructions on its use. They will subsequently be followed up for up to six months. Every two weeks, participants will fill out a follow-up questionnaire on mouthwash use and sexual activities and self-collect oral rinse sample to be returned by mail.

Conditions

• Human Papilloma Virus

Interventions

Type	Name	Description
OTHER	Mouthwash gargling	15 - 20 ml of mouthwash to be gargled vigorously for 30 to 60 seconds daily (morning and night) as an adjunct to regular toothbrushing, and before and/or immediately after sexual activities.

Timeline

• Start date: 2023-05-26
• Primary completion: 2023-12-01
• Completion: 2024-03-01
• First posted: 2023-02-28
• Last updated: 2023-06-22

Locations

1 site across 1 country: Canada