Trials / Recruiting
RecruitingNCT05746650
Improving Tissue Repair After Injury in the Muscle-tendon Interface Muscle Tissue Injury
Regulation of Protein Turnover in Connective Tissue From Muscle and Tendon Following Muscle Tissue Injury
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- Bispebjerg Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 35 Years
- Healthy volunteers
- Accepted
Summary
The study is a 2-week human study where 40 patients who are scheduled to undergo reconstructive knee surgery are randomized to administration of GH or placebo following or without neuromuscular electrical stimulation of hamstring muscles.The overall aim is to determine, the role of muscle connective tissue protein synthesis in muscle injury and repair.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Electrical stimulation | Experimentally induced muscly injury via. neuromuscular electrical stimulation of the hamstring muscles |
| DRUG | Growth hormone (somatropin) | Daily injection of growth hormone |
| OTHER | Control (No electrical stimulation, nor growth hormone) | No electrical stimulation, nor growth hormone |
Timeline
- Start date
- 2023-02-24
- Primary completion
- 2027-06-01
- Completion
- 2027-09-01
- First posted
- 2023-02-28
- Last updated
- 2025-09-24
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT05746650. Inclusion in this directory is not an endorsement.