NCT05745220

Influence of Silicone Hydrogel Contact Lens Neophyte Wear on Corneal Sensitivity

Corneal Sensitivity in Silicone Hydrogel Contact Lens Wear

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (actual)
• Sponsor: Daniela Nosch · Academic / Other
• Sex: All
• Age: 18 Years – 38 Years
• Healthy volunteers: Accepted

Summary

Soft contact lenses can affect the ocular surface and sometimes cause intolerance. The aim of this study is to measure corneal sensitivity using the Swiss Liquid Jet aesthesiometer at baseline, after one and after six weeks, in novice daily contact lens wearers.

Detailed description

Contact lens discomfort is described by many wearers. Wearing contact lenses can influence corneal sensitivity through three mechanisms: hypoxic, mechanical and inflammatory. A change in corneal sensitivity can be considered an indicator of a change in corneal physiology. Corneal sensitivity plays a major role in maintaining eye health. The interest of this study is to test the variability of the corneal sensitivity threshold during a new adaptation of silicone hydrogel contact lenses, and to verify whether there is a correlation with the wearer's comfort. For that, corneal sensitivity threshold measurements are taken at the baseline and then after one and six weeks of daily contact lens wear. The measurement is performed with the Swiss Liquid Jet aesthesiometer for corneal sensitivity (SLACS). After one week and six weeks of daily lens wear, participants complete a Contact Lens Dry Eye Questionnaire (CLDEQ-8) for comfort analysis.

Conditions

• Cornea

Interventions

Type	Name	Description
OTHER	Device: silicone hydrogel contact lens	Silicone hydrogel contact lens

Timeline

• Start date: 2023-04-08
• Primary completion: 2023-09-30
• Completion: 2023-09-30
• First posted: 2023-02-27
• Last updated: 2024-02-26

Locations

1 site across 1 country: Switzerland