NCT05744609

Predicting Severe Outcomes Among Children Hospitalized With Community-acquired Pneumonia

Development and Validation of a Risk Score for Predicting Severe Outcomes Among Children Hospitalized With Community-acquired Pneumonia

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 6,000 (actual)
• Sponsor: Children's Hospital of Fudan University · Academic / Other
• Sex: All
• Age: 29 Days – 18 Years
• Healthy volunteers: Not accepted

Summary

In this study, investigators aimed to develop and validate a risk score to predict severe outcomes (e.g., mortality and ICU admission) in children who were admitted to the Children's Hospital of Fudan University between 2017 and 2022 due to community-acquired pneumonia (CAP). The objectives were as follows. 1. Develop a risk prediction model based on demographic, comorbidity, clinical characteristics, laboratory data, and chest radiographic reports to predict severe outcomes among children hospitalized with CAP; 2. Develop a risk scoring system and determine the cut-off point; 3. Externally validate the easy-to-use risk score.

Conditions

• Pneumonia
• Child
• Prognosis

Interventions

Type	Name	Description
OTHER	exposures of interest: epidemiological data, clinical characteristics, laboratory data, and chest radiographic reports	epidemiological data (e.g., age, sex, and residential area), clinical characteristics (e.g., fever, cough, and wheeze), laboratory data (e.g., white blood cell, c-reaction protein, and procalcitonin), and chest radiographic reports (e.g., X-ray, CT, and ultrasound)

Timeline

• Start date: 2017-01-01
• Primary completion: 2022-12-31
• Completion: 2022-12-31
• First posted: 2023-02-27
• Last updated: 2023-02-27

Locations

1 site across 1 country: China