Clinical Trials Directory

Trials / Completed

CompletedNCT05743790

The Role of Dietary Intake and Host Genetics in Gut Microbiome Response to Resistant Starch Consumption

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
196 (actual)
Sponsor
Cornell University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

Resistant starch (RS), a type of dietary fiber, was shown to have beneficial effects on human health through its impact on microbes present in the intestine. However, the effects of RS on the gut microbiota and in turn, on human health, can vary between individuals. Consequently, everyone may not reap the same health benefits by eating high amounts of RS. Factors predicting how an individual's gut microbes as well as the beneficial metabolites produced by these microbes respond to RS supplementation would be helpful in developing precision nutrition approaches that maximize the benefits of dietary fiber intake. The objective of this study was to evaluate candidate predictors of gut microbiota response to RS supplementation.

Conditions

Interventions

TypeNameDescription
DIETARY_SUPPLEMENTRS2-control-RS4Group A: Treatment 1 = RS2 (Hi-Maize 260), Treatment 2 = Control (Amioca TF), Treatment 3 = RS4 (Versafibe 1490)
DIETARY_SUPPLEMENTRS4-control-RS2Group B: Treatment 1 = RS4 (Versafibe 1490), Treatment 2 = Control (Amioca TF), Treatment 3 = RS2 (Hi-Maize 260)

Timeline

Start date
2019-09-26
Primary completion
2020-12-15
Completion
2020-12-15
First posted
2023-02-24
Last updated
2023-04-03

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT05743790. Inclusion in this directory is not an endorsement.