Trials / Completed
CompletedNCT05743361
Security Efficacy COVID-19 Vaccination
Studio Sierologico in Volontari Vaccinati Contro COVID-19
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 540 (actual)
- Sponsor
- Istituto Auxologico Italiano · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Preliminary data support a possible molecular mimicry between SARS-CoV-2 and autologous components. This suggests the occurrence of autoimmunity during COVID-19. Consistently, autoimmunity may occur after SARS-CoV2 vaccination. The study aims to investigate the production of autoantibodies after vaccination in healtcare workers.
Detailed description
Healtcare workers undergoing SARS-CoV-2 vaccination (with RNA-vaccines) will be included on a voluntary basis. Blood samples will be collected before and after vaccination (1 -3 - 6 - 12 months). All the vaccination side effects will be registered.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Blood sampling | Detection of ANA, AMA, anti-dsDNA, anti-ENA, anti-MPO, anti-PR3, aPL, RF, ACPA, anti- TPO, anti-TG |
Timeline
- Start date
- 2021-01-07
- Primary completion
- 2021-12-31
- Completion
- 2022-04-30
- First posted
- 2023-02-24
- Last updated
- 2023-02-24
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT05743361. Inclusion in this directory is not an endorsement.