NCT05742204

Plasma Proteomic Biomarkers for Early Diagnosis of Lung Cancer

Identification and Functional Verification Study in Plasma Proteomic Biomarkers for Early Diagnosis of Lung Cancer

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 3,700 (estimated)
• Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

We will identify plasma proteomics biomarkers for early diagnosis of lung cancer.

Detailed description

We will use TMT-based proteomics approaches to analyze more than 2000 proteins in plasma samples from lung cancer patients and controls. Artificial intelligent (AI) assisted proteomics classifier will be developed for early diagnosis of lung cancer.

Conditions

• Lung Cancer

Interventions

Type	Name	Description
OTHER	Plasma protein biomarker analysis	Plasma samples from lung cancer patients were collected at the time of their diagnosis, prior to the initiation of treatment.We will use TMT-based proteomics approaches to analyze more than 2000 proteins in plasma samples from lung cancer patients .
OTHER	Plasma protein biomarker analysis	Plasma samples of control subjects were collected.

Timeline

• Start date: 2023-02-01
• Primary completion: 2025-05-01
• Completion: 2032-10-31
• First posted: 2023-02-23
• Last updated: 2025-05-15

Locations

1 site across 1 country: China