Trials / Completed
CompletedNCT05741229
The Effect Of Nebulizied Nitroglycerin As An Adjuvant Therapy For Persistent Pulmonary Hypertension Of Newborns
The Effect Of Nebulizied Nitroglycerin As An Adjuvant Drug In Management Of Persistent Pulmonary Hypertension Of Newborns
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 80 (actual)
- Sponsor
- Alexandria University · Academic / Other
- Sex
- All
- Age
- 1 Hour – 7 Days
- Healthy volunteers
- Not accepted
Summary
This aim of the study is to evaluate the effect of nebulized nitroglycerin on echocardiographic (biventricular function, pulmonary artery pressure, PDA and PFO shunting and tissue doppler imaging) and clinical parameters (Oxygen saturation index, heart rate, blood pressure, mean airway pressure, ventilation setting) in patients with PPHN.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Nebulized nitroglycerine as adjunctive therapy | Patients with PPHN will have nebulized nitroglycerine as adjunctive therapy |
| DRUG | conventional therapy for PPHN | patients will receive sildenafil which is used routinely in management of PPHN in our unit, in addition to appropriate oxygenation and ventilation. |
Timeline
- Start date
- 2024-01-01
- Primary completion
- 2024-12-30
- Completion
- 2025-01-20
- First posted
- 2023-02-23
- Last updated
- 2025-06-29
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT05741229. Inclusion in this directory is not an endorsement.