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Trials / Active Not Recruiting

Active Not RecruitingNCT05739435

Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis

A Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Patients With Plaque Psoriasis

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
165 (actual)
Sponsor
Alumis Inc · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a multi-center, open-label extension (OLE) study in patients with plaque psoriasis who have completed their participation in a previous plaque psoriasis study of ESK-001.

Detailed description

This study will consist of patients who have completed their participation in a previous plaque psoriasis study of ESK-001. Each patient will be assigned to receive ESK-001 at one of two open-label dose levels. Patients have the option to remain on study until ESK-001 is commercially available.

Conditions

Interventions

TypeNameDescription
DRUGenvudeucitinibOral tablet

Timeline

Start date
2023-01-17
Primary completion
2026-12-01
Completion
2026-12-30
First posted
2023-02-22
Last updated
2026-04-01

Locations

38 sites across 2 countries: United States, Canada

Regulatory

Source: ClinicalTrials.gov record NCT05739435. Inclusion in this directory is not an endorsement.