NCT05738928

Microbiological Profile of VAP Patients in Respiratory ICU

Microbiological Profile of Ventilator Associated Pneumonia in Respiratory Intensive Care Unit of Assiut University Hospital

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 86 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Identification of the microbial profile of Ventilator associated pneumonia causing microorganisms among Respiratory ICU patients .

Detailed description

Ventilator-associated pneumonia (VAP) is one of the common serious infectious diseases encountered in the intensive care unit (ICU), which highly affects the healthcare cost and patient prognosis. All-cause of mortality associated with VAP has been reported to range from 20% to 50%. The etiology of VAP and their antimicrobial susceptibility pattern varies with different patient populations and types of ICUs. VAP may be caused by a wide spectrum of bacterial pathogens, which may be polymicrobial and are rarely due to viral or fungal pathogens in immune-competent hosts. Common etiologic agents are Gram-negative bacilli such as Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, and Acinetobacter spp. and Staphylococcus aureus among Gram-positive cocci. Due to the increased incidence of MDR organisms in Intensive Care Units (ICUs), early and correct diagnosis of VAP is mandatory for optimal antibiotic therapy. The frequency of specific MDR pathogens causing VAP varies in hospitals, patient populations. Also varies according underlying disease. this study will be conducted in respiratory intensive care unit, chest disease and tuberculosis department at Assiut university hospitals.

Conditions

• VAP - Ventilator Associated Pneumonia

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	blood and sputum culture	Noninvasive sampling ( Endo Tracheal Aspiration) for staining and culture. Blood culture .

Timeline

• Start date: 2023-02-01
• Primary completion: 2023-12-01
• Completion: 2024-02-01
• First posted: 2023-02-22
• Last updated: 2023-02-22