Trials / Recruiting
RecruitingNCT05736614
Optimizing PrEP Uptake and Adherence Among Male Sex Workers
Efficacy of a PrEP Uptake & Adherence Intervention Among Male Sex Workers Using a 2-stage Randomization Design
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 500 (estimated)
- Sponsor
- Brown University · Academic / Other
- Sex
- Male
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
"PrEPare for Work" is a randomized controlled trial (RCT) whose goal is to test the efficacy of a behavioral intervention (Short Title: PrEPare for Work) in improving PrEP uptake, adherence, and persistence among male sex workers (MSW)
Detailed description
A theory-based, manualized intervention -called "PrEPare for Work"-includes two separate but complementary interventions that address MSW-specific behavioral, economic, interpersonal \& structural-level barriers to accessing and adhering to PrEP: 1) peer-led, strengths-based case management (SBCM) for PrEP linkage and uptake; and 2) a technology and counseling intervention to optimize PrEP adherence (once they have access to PrEP). This research will test the PrEPare for Work intervention in a fully-powered RCT to assess efficacy and cost-effectiveness.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Stage 1 Strength Based Case Management (SBCM) Condition | Intervention participants will receive a trained SBCM to motivate, support, and assist in linkage to PrEP prescribers to help facilitate obtaining PrEP medication to initiate treatment. |
| BEHAVIORAL | Stage 2 PrEPare for Work Intervention Condition | Intervention participants will receive 1-on-1 adherence counseling and personalized daily text messaging reminders to increase PrEP adherence. Intervention participants will undergo three adherence intervention sessions (once per week for 3 weeks) with interventionist. |
Timeline
- Start date
- 2022-11-03
- Primary completion
- 2026-06-01
- Completion
- 2026-06-01
- First posted
- 2023-02-21
- Last updated
- 2025-05-09
Locations
5 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT05736614. Inclusion in this directory is not an endorsement.