NCT05736250

Establishment of a Method for Extraction and Quantification of Gingival Tissue Nicotine y

Establishment of a Method for Extraction and Quantification of Gingival Tissue Nicotine in Relation to Conventional Tobacco Biomarkers: a Pilot Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 20 (estimated)
• Sponsor: University of Liege · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Accepted

Summary

establishment of a method for extraction and quantification of gingival tissue nicotine in relation to conventional tobacco biomarkers: a pilot study

Detailed description

The study aim to establish a method for extraction and quantification of gingival tissue nicotine. Additionnaly, the relationship between the nicotine tissue intoxication with others smoking indicators will be evaluated as mentionned in the following PICO question: * P: Smoker patients * I: Biopsie of gingival tissue * C: Non-smoker patient * O: nicotine dependence test (FTND), salivary cotinine, fibroblast nicotine, number of cigarette consumed per day (NCC) and the pack-year (PY)

Conditions

• Smoking, Cigarette

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	biopsie	gingival biopsie

Timeline

• Start date: 2022-01-14
• Primary completion: 2023-06-01
• Completion: 2023-06-01
• First posted: 2023-02-21
• Last updated: 2023-02-21

Locations

1 site across 1 country: Belgium