Trials / Recruiting
RecruitingNCT05734430
Genetics of Appendix Cancer Study
Genetics of Appendix Cancer: The GAP Study
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 700 (estimated)
- Sponsor
- Andreana Holowatyj, PhD, MSCI · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The GAP Study is a prospective cohort study designed to comprehensively investigate genetic variations that may contribute to cancer development among individuals diagnosed with appendix/appendiceal cancer who are ages 18+ years.
Detailed description
The Genetics of Appendix Cancer (GAP) Study aims to analyze hereditary factors, tumor characteristics and clinical features/outcomes among adults diagnosed with appendix cancer and their biological parents. Patients are recruited at any time after a diagnosis of appendix cancer and followed for up to 6 years after study enrollment. This cohort is enriched by robust biospecimens and data collections.
Conditions
- Appendix Cancer
- Appendiceal Cancer
- Appendiceal Neoplasms
- Appendiceal Mucinous Neoplasm
- Appendiceal Adenocarcinoma
- Appendiceal Carcinoid Tumor
- Appendiceal Neoplasm Malignant Secondary
- Appendix Adenocarcinoma
- Appendix Mucinous Neoplasm
- Appendix Tumor
- Appendix Cancer Metastatic
- Appendix NET
- Low-Grade Appendix Mucinous Neoplasm
- High Grade Appendix Mucinous Neoplasm
- High Grade Appendix Mucinous Adenocarcinoma
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | Genetic profiling | Whole exome sequencing |
| OTHER | Retrospective tissue procurement | Collection of archived fixed-formalin, paraffin-embedded (FFPE) primary appendix tumor tissues that were previously removed |
Timeline
- Start date
- 2022-11-11
- Primary completion
- 2032-11-01
- Completion
- 2034-11-01
- First posted
- 2023-02-21
- Last updated
- 2025-04-18
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05734430. Inclusion in this directory is not an endorsement.