NCT05734261

Forced Oscillations Technique During a Metacholine Test in Children

Interest of Forced Oscillations During a Methacholine Test in Children

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 112 (estimated)
• Sponsor: University Hospital, Montpellier · Academic / Other
• Sex: All
• Age: 6 Years – 16 Years
• Healthy volunteers: Not accepted

Summary

Asthma is the most common chronic lung disease in children. It affects more than 1 in 10 children in France. The methacholine bronchial challenge test (MBT) is indicated to assess the probability of asthma suggested by clinical symptoms by measuring the forced expiratory volume in one second (FEV1), after inhalation of a cumulative dose of methacholine. In children, the measurement of FEV1 requires a high level of cooperation from the child, which can be the source of false negatives or no result if this is not obtained. The objective of this study is to evaluate if the measurement of the respiratory function by the forced oscillations technique, allows to predict the variation of the FEV1 obtained

Conditions

• Asthma in Children

Interventions

Type	Name	Description
PROCEDURE	Airway Oscillation System	After each methacholine dose administred, respiratory function will be measured by forced oscillation

Timeline

• Start date: 2023-09-07
• Primary completion: 2026-02-15
• Completion: 2026-12-30
• First posted: 2023-02-17
• Last updated: 2023-09-13

Locations

1 site across 1 country: France