NCT05731596

Comparative Clinical Study to Evaluate the Efficacy and Safety of Rosuvastatin Vs CoQ10 on Nonalcoholic Steatohepatitis

Comparative Clinical Study to Evaluate the Possible Efficacy and Safety of Rosuvastatin Versus Coenzyme Q10 on Nonalcoholic Steatohepatitis

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 46 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will be a randomized, controlled, parallel study that aims to evaluate the efficacy and safety of Rosuvastatin versus Coenzyme Q10 on nonalcoholic steatohepatitis patients.

Detailed description

* This study will be a randomized, controlled, parallel study. * It will be conducted on 46 patients diagnosed with NASH * The patients will be randomized into two groups: Group 1(n=23): patients will receive Rosuvastatin 20mg/day orally Group 2(n=23): patients will receive Coenzyme Q10 100 mg/day orally The patients will be selected from community awareness campaigns about NASH in Alexandria , Egypt . Written informed consent will be obtained from all patients. This study will be approved by the Research Ethics Committee of Tanta University and Alexandria university. The study duration will be 3 months.

Conditions

• Nonalcoholic Steatohepatitis

Interventions

Type	Name	Description
DRUG	Rosuvastatin 20 Mg Oral Tablet	Rosuvastatin 20 mg will be administered orally once daily for 3 Months
DRUG	Coenzyme Q10 100 MG Oral Capsule	Coenzyme Q10 100 mg will be administered orally once daily for 3 Months

Timeline

• Start date: 2023-06-01
• Primary completion: 2024-02-01
• Completion: 2024-04-01
• First posted: 2023-02-16
• Last updated: 2023-05-16