Trials / Completed
CompletedNCT05731089
IVI Aflibercept Before and After Phaco in DME.
Pre-Operative Versus Post-Operative Intravitreal Aflibercept Injection for Management of DME in Patients Undergoing Cataract Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- Al Hadi Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To study whether or not cataract surgery should be deferred until treating the co-existing diabetic macular edema (DME) using intravitreal (IVI) anti-vascular endothelial growth factor (anti-VEGF).
Detailed description
A prospective randomized interventional study included diabetic patients with visually significant cataract and DME. Patients were divided into 2 groups. Group A received three pre-operative intravitreal Aflibercept injections with a monthly interval, the third injection was given intra-operatively. Group B received a single intra-operative injection, and two post-operative injections with a monthly interval. follow up for 6 months.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Phacoemulsification with IVI of aflibercept | IVI was either before or after cataract surgery |
Timeline
- Start date
- 2019-09-01
- Primary completion
- 2022-08-01
- Completion
- 2022-12-01
- First posted
- 2023-02-16
- Last updated
- 2023-02-16
Locations
1 site across 1 country: Kuwait
Source: ClinicalTrials.gov record NCT05731089. Inclusion in this directory is not an endorsement.