Trials / Unknown
UnknownNCT05728788
Correlation Between Myocardial Injury and Intestinal Flora Changes Associated With Oncology Drug Therapy
Correlation Between Early Myocardial Injury and Intestinal Flora Changes Associated With Oncology Drug Therapy
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (estimated)
- Sponsor
- Peking University Third Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study was to explore the relationship between early myocardial injury caused by tumor drug therapy and intestinal microbial structure changes by echocardiographic two-dimensional speckle tracking technique and intestinal microflora structure detection.
Detailed description
This is a monocentric prospective cohort study in which 50 patients treated for malignant tumors will be included. All participants will be followed for 6 months after the initiation of oncology drug therapy. Echocardiography and 2D speckle tracking will be performed and stool and blood samples will be tested before treatment initiation and at 3 and 6 months after initiation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Antitumor drugs | Anthracyclines, immune checkpoint inhibitors, monoclonal antibodies, and tyrosine kinase inhibitors |
Timeline
- Start date
- 2022-07-01
- Primary completion
- 2023-06-01
- Completion
- 2023-12-01
- First posted
- 2023-02-15
- Last updated
- 2023-03-03
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT05728788. Inclusion in this directory is not an endorsement.