Clinical Trials Directory

Trials / Unknown

UnknownNCT05727397

Efficacy and Safety of RC28-E Versus Aflibercept

A Randomized, Double-Masked, Multicenter, Two-Arm Study Comparing the Efficacy and Safety of RC28-E 2mg Versus Aflibercept in Subjects With Wet Age-Related Macular Degeneration

Status
Unknown
Phase
Phase 3
Study type
Interventional
Enrollment
432 (estimated)
Sponsor
RemeGen Co., Ltd. · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

This is a randomized, double-masked, multicenter study comparing the the efficacy and safety of RC28-E injection (a chimric decoy receptor trap fusion protein by dual blockage of VEGF and FGF-2) versus aflibercept in patients with wet age-related macular degeneration.

Conditions

Interventions

TypeNameDescription
DRUGRC28-EOphthalmic solution for intravitreal injection administered as a 2.0mg/50 µL dose.
DRUGAfliberceptOphthalmic solution for intravitreal injection administered as a 2.0mg/50 µL dose.

Timeline

Start date
2023-03-14
Primary completion
2025-11-29
Completion
2025-12-29
First posted
2023-02-14
Last updated
2023-08-31

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05727397. Inclusion in this directory is not an endorsement.