NCT05724992

Familial Pancreatic Cancer PROPHilation Program in Italy

Standardised Genetic Profiling of Subjects Belonging to the Italian Multicenter Registry of Prospective Surveillance of Subjects at Genetic Risk of Pancreatic Cancer

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 3,000 (estimated)
• Sponsor: Associazione Italiana per lo Studio del Pancreas · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The goal of the PROPH-ITA Study is to perform genetic testing in family members of pancreatic cancer patients who may have a genetic predisposition. The subjects belong to the Italian Registry of Families At Risk of Pancreatic Cancer (IRFARPC, #NCT04095195). This investigational study will assess the genetic background of subjects with familiarity with pancreatic cancer only. Participants may accept to undergo genetic testing as part of the IRFARPC registry, through a saliva-swab-based 41-gene panel test. Up to 3,000 participants will be enrolled in this study.

Conditions

• Candidates for Hereditary Pancreatic Cancer Testing

Interventions

Type	Name	Description
GENETIC	Saliva swab testing	41 pancreatic cancer predisposition genes will be tested through a saliva-based swab

Timeline

• Start date: 2022-12-20
• Primary completion: 2027-12-20
• Completion: 2028-12-20
• First posted: 2023-02-13
• Last updated: 2023-02-15

Locations

1 site across 1 country: Italy