Clinical Trials Directory

Trials / Completed

CompletedNCT05723627

Comparison of Remimazolam and Propofol Effect on Oxygenation Reservoir During Diagnostic Gastric Endoscopy

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
70 (actual)
Sponsor
Yonsei University · Academic / Other
Sex
All
Age
19 Years – 80 Years
Healthy volunteers
Accepted

Summary

Propofol is one of the most commonly used sedative in endoscopic procedures, while its potency to induce respiratory depression may threaten patient safety. Remimazolam is known to less likely induce hemodynamic instability when compared to propofol, yet its favorable effects are not clearly evaluated in endoscopic procedures. Hence, this study aimed to compare hemodynamic effects of remimazolam and propofol, by evaluating oxygen reserve index (ORI) in patients scheduled for diagnostic gastric endoscopy.

Conditions

Interventions

TypeNameDescription
DRUGRemimazolam besylatePatients in this group receives 0.1mg/kg of remimazolam to induce sedation prior to endoscope insertion.
DRUGPropofolPatients in this group receives 0.5mg/kg of propofol to induce sedation prior to endoscope insertion.

Timeline

Start date
2023-04-06
Primary completion
2023-09-21
Completion
2023-09-21
First posted
2023-02-13
Last updated
2023-12-08

Locations

1 site across 1 country: South Korea

Source: ClinicalTrials.gov record NCT05723627. Inclusion in this directory is not an endorsement.