NCT05720013

Acute Effects of Beetroot Juice on Locomotor Economy and Capacity in Chronic Stroke

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Indiana University · Academic / Other
• Sex: All
• Age: 18 Years – 89 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate if a beetroot juice supplement can improve oxygen capacity during walking tasks at a submaximal and maximal effort in people greater than 6 months following stroke.

Detailed description

During this study, participants will perform baseline measurements such as walking and balance tests. During baseline testing, participants will be asked to perform a maximal exertion test while walking on a treadmill to determine the speed for a submaximal walking test. One week after baseline testing, the participant will have an intervention session where they drink either a beetroot juice supplement or a placebo. The placebo will taste similar to the beetroot juice and participants may not be able to tell the difference between the two different supplements. After a week, the participant will return to the lab and drink the other supplement. For example, if the participant drank the beetroot juice in the first session, then they will drink the placebo in the second session. During each intervention session, the participant will be asked to perform two treadmill tests, one with submaximal effort and one with maximal effort. After the walking tests, they will drink either the beetroot juice or placebo and have their blood drawn. They will wait at the hospital for 2-3 hours and have their blood drawn again. The participants will then complete the two treadmill tests again. The two intervention sessions will last about 4-6 hours for each session. Participation in the study will last 4-6 weeks including screening and baseline testing.

Conditions

• Stroke
• CVA

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Beetroot Juice supplement	The experimental arm includes orally ingesting 140 mL Beet-It Sport Nitrate 400.
DIETARY_SUPPLEMENT	Placebo supplement	he placebo arm involves orally ingesting a 140 mL placebo solution with the dietary nitrate removed.

Timeline

• Start date: 2023-02-01
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2023-02-09
• Last updated: 2024-05-22

Locations

1 site across 1 country: United States