NCT05718466

Stereotactic Radiology Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-Line Chemotherapy

Prospective Study of Stereotactic Radiosurgery Using Diffusion-Weighted Abnormality Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-line Chemotherapy

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: Henry Ford Health System · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

This clinical trial is a prospective study of radiosurgery treatment for progressive GBM to test 1)the efficacy of radiosurgery for recurrent/progressive GBM compared to chemotherapy , and 2) the role of diffusion-weighted image (DWI) to predict the early tumor progression and treatment response.

Conditions

• Recurrent or Progressive Glioblastoma

Interventions

Type	Name	Description
DRUG	Bevacizumab
DRUG	Chemotherapy
RADIATION	Fractionated radiosurgery

Timeline

• Start date: 2010-11-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2023-02-08
• Last updated: 2023-07-17
• Results posted: 2023-07-17

Locations

1 site across 1 country: United States