NCT05717855

Screening of Septo-optic Dysplasia During a Fetal Examination at 16-20 Weeks of Gestation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: Gaziosmanpasa Research and Education Hospital · Other Government
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Evaluation of prenatal optic chiasm (OC) is important for the differential diagnosis of septo-optic dysplasia (SOD), which is a congenital optic disc anomaly, and the absence of the cavum septum pellucidum (CSP). Septo-optic dysplasia is associated with a wide range of neurological abnormalities, including hypoplasia of the visual pathways, CSP agenesis, and developmental delay.

Detailed description

Up to now, optic chiasm measurement were all done in the third trimester. in the present study, OC will be measure directly in a 2D ultrasound in coronal plane within the second trimester. In fetuses with SP agenesis, the morphology and width of the OC visual pathway may be a suitable tool to assess its development. It can also assist in the difficult task of providing prenatal counseling when faced with a diagnosis of CP agenesis. therefore In the present study, it was planned to show the optic chiasm in the screening of septooptic dysplasia by ultrasound between 16-20 weeks of gestation, and to measure the optic chiasma width and length, and to determine the mean values in the second trimester.

Conditions

• 2D Ultrasound
• Cavum Septum Pellucidum
• Septooptic Dysplasia
• Optic Chiasma
• Willis Polygon

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Displaying optic chiasm for screening septooptic dysplasia	Displaying and measuring the width and length of the optic chiasm for screening septooptic dysplasia with ultrasound between 16-20 weeks of gestation

Timeline

• Start date: 2020-09-21
• Primary completion: 2021-03-21
• Completion: 2021-04-21
• First posted: 2023-02-08
• Last updated: 2023-02-08

Locations

1 site across 1 country: Turkey (Türkiye)