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Trials / Active Not Recruiting

Active Not RecruitingNCT05716087

A Study of Rocbrutinib in Participants With Relapse or Refractory Mantle Cell Lymphoma

An Open Label, Single Arm, Multicenter Phase II Study of the Efficacy and Safety of Rocbrutinib Monotherapy for Recurrent or Refractory Mantle Cell Lymphoma

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
62 (estimated)
Sponsor
Guangzhou Lupeng Pharmaceutical Company LTD. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is an open-label, single arm, multi-center Phase 2 study of oral Rocbrutinib in patients with mantle cell lymphoma who are failed or relapsed after remission or intolerated to Bruton's tyrosine kinase (BTK) inhibitor.

Conditions

Interventions

TypeNameDescription
DRUGRocbrutinibSubjects to take Rocbrutinib tablets orally with 240mL water, without food, Once daily.The treatment will continue until progressive disease, unacceptable toxicity, etc.

Timeline

Start date
2023-02-21
Primary completion
2024-12-05
Completion
2026-06-30
First posted
2023-02-08
Last updated
2026-01-15

Locations

43 sites across 1 country: China

Regulatory

Source: ClinicalTrials.gov record NCT05716087. Inclusion in this directory is not an endorsement.

A Study of Rocbrutinib in Participants With Relapse or Refractory Mantle Cell Lymphoma (NCT05716087) · Clinical Trials Directory