Clinical Trials Directory

Trials / Completed

CompletedNCT05715723

Study of Safety and Efficiency of the Drug Reamberin® in the Intensive Care of Patients With Acute Ethanol Intoxication

Non-interventional, Prospective Study of Safety and Efficiency of the Drug Reamberin® in the Intensive Care of Patients With Acute Ethanol Intoxication: Hospital Practice

Status
Completed
Phase
Study type
Observational
Enrollment
296 (actual)
Sponsor
POLYSAN Scientific & Technological Pharmaceutical Company · Industry
Sex
All
Age
22 Years – 65 Years
Healthy volunteers
Not accepted

Summary

Acute ethanol intoxication is the most frequent pathologic condition developing in subjects using alcohol. The severity of disorders in acute alcohol intoxication is determined, first of all, by the quantity of consumed alcohol and the duration of the toxic effect. When toxic doses of alcohol are taken per os, a life-threatening condition develops, which is manifested by consciousness depression and severe metabolism disorders. Reamberin (1.5 % meglumine sodium succinate solution) is an infusion solution with a balanced electrolyte composition and succinic acid, which is recommended for rehydration and detoxication in patients with intoxications of different genesis. The metabolic effect of Reamberin helps restore homeostasis and improve the natural organism detoxication. The investigators suppose that administration of Reamberin to patients with acute ethanol intoxication will make it possible to improve the treatment quality as compared to the standard therapy.

Detailed description

All drugs will be administered according to the instruction for medical use and conventional clinical practice. The decision on the selection of therapy shall be made by a medical investigator irrespective of the protocol before the inclusion of a patient in the study.

Conditions

Interventions

TypeNameDescription
DRUGReamberinReamberin® in the average daily dose of 10 ml/kg daily

Timeline

Start date
2022-09-15
Primary completion
2024-11-01
Completion
2025-02-28
First posted
2023-02-08
Last updated
2025-04-18

Locations

18 sites across 1 country: Russia

Source: ClinicalTrials.gov record NCT05715723. Inclusion in this directory is not an endorsement.