NCT05714462

Effects of Beef Consumption on Skeletal Muscle Protein Homeostasis and Inflammatory Factors in Pre- and Postmenopausal Females

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 65 (actual)
• Sponsor: University of Arkansas · Academic / Other
• Sex: Female
• Age: 35 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This will be a randomized study to determine if animal-based protein-rich food sources can stimulate greater muscle protein turnover and whole-body protein balance and reduce skeletal muscle inflammatory markers in postmenopausal women compared to vegetarian base protein-rich foods.

Detailed description

A randomized cross-sectional controlled trial will be conducted to quantify whole-body and muscle protein turnover and skeletal muscle inflammation following 5-days of consumption of either beef or isonitrogenous plant-based sources of protein in normal/overweight and obese post-menopausal females. A premenopausal normal/overweight group consuming beef containing study meals will also be recruited to serve as a healthy control comparison.

Conditions

• Menopause Related Conditions

Interventions

Type	Name	Description
OTHER	meals consisting of primarily animal protein sources	an omnivorous diet
OTHER	meals consisting of plant protein sources	an herbivorous diet

Timeline

• Start date: 2023-08-28
• Primary completion: 2025-04-01
• Completion: 2025-04-01
• First posted: 2023-02-06
• Last updated: 2025-05-06

Locations

1 site across 1 country: United States