NCT05712811

Comparison of Cryotherapy and Peeling Agent in the Treatment of Common Warts

Cryotherapy Versus Topical Tricholoacetic Acid 90% in Treatment of Common Warts

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Combined Military Hospital Abbottabad · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Objective: To compare the efficacy of cryotherapy using liquid nitrogen (cryoget method) versus trichloroacetic acid 90% (applicator method) in treatment of common warts. Study Design: Randomized Control Trial. Place And Duration of Study: Department of Dermatology, CMH Abbottabad from Jun 2022 to Nov, 2022.

Detailed description

A total of 60 patients were enrolled in this investigation by non-probability consecutive sampling technique. Sample size was calculated using WHO sample size calculator and patients were randomized into two equal groups, A and B, each comprising of 30 patients through lottery method. Patients with common warts such as hard lesions, raised lumps with rough surfaces at the back of their fingers, around nails and palm of their hands between the ages of 18 and 60 were included, whereas those with genital warts, cardiac, hepatic, renal, or hypercholesterolemia were excluded.

Conditions

• Warts

Interventions

Type	Name	Description
DRUG	CRYOTHERAPY	Group A had their warts treated once every two weeks for a total of twelve weeks, with liquid nitrogen using cryoget method for 10 to 15 seconds on each lesion (depending on size, until a narrow white rim of around 1 mm developed around it).
DRUG	Tricholoracetic acid	Group B were treated with liquid TCA 90% by an applicator every two weeks for a total of twelve weeks. After 20 minutes, patients were instructed to remove the solution by washing their warts with water or regular saline.

Timeline

• Start date: 2022-06-01
• Primary completion: 2022-11-30
• Completion: 2022-11-30
• First posted: 2023-02-06
• Last updated: 2023-02-06

Locations

1 site across 1 country: Pakistan