NCT05712759

Nosocomial Influenza Surveillance of 2022 - 2027 Seasonal Period

Surveillance of Nosocomial Influenza at Edouard Herriot University Hospital, Lyon, France

• Status: Withdrawn
• Phase: —
• Study type: Observational
• Enrollment: 0 (actual)
• Sponsor: Hospices Civils de Lyon · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Hospital-Acquired Influenza (HAI) is closely linked to the intensity of influenza in the community. HAI is associated with significant morbidity, mortality and extra costs due to prolonged hospital stay. The incidence of laboratory confirmed HAI has been reported rarely. The proportion of HAI among influenza cases was 11.38% (95% Confidence Interval: 5.19%-19.55%) in a meta-analysis of 14 studies. In France, a prospective surveillance study of adults with Influenza-Like Illness (ILI) over 11 years, reported that 35.6% of the influenza cases diagnosed at hospital were hospital-acquired. HAI is transmitted via respiratory droplets and by hand contacts. The spread is facilitated by Health Care Professionals (HCPs), patients and visitors. Prevention and control of HAI is of upmost importance to preserve patient safety and limit the related economic costs. While vaccination of HCPs has been shown to contribute to the reduction of HAI, less is known on the impact of patient vaccination on the risk of HAI during hospitalization. The aim of this study is to describe the hospital-acquired influenza in a french university hospital.

Conditions

• Infection Viral

Interventions

Type	Name	Description
OTHER	Influenza-like illness group	Each patient who present ILI (influenza-like illness) at admission or during hospitalization and who have had a nasopharyngeal swab taken as part of their care for the purpose of diagnosing influenza by Polymerase Chain reaction (PCR) testing. ILI is defined by fever \> 37,8°C or/and cough or sore throat.

Timeline

• Start date: 2025-03-09
• Primary completion: 2025-03-09
• Completion: 2025-03-09
• First posted: 2023-02-03
• Last updated: 2025-03-11