NCT05712616

Role of Strontium Ranelate in Proximal Femur Fragility Fractures.

Role of Strontium Ranelate in Radiological Healing of Proximal Femur Fractures. A Phase IV Double Blinded Randomized Controlled Trial

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Aga Khan University Hospital, Pakistan · Academic / Other
• Sex: All
• Age: 60 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

This study is being conducted with the aim of comparing the time to bone healing after surgery for fragility fractures of proximal femur between patients receiving strontium ranelate and placebo. Patients recruited are of 60 years of age and above. Bone healing will be assessed on clinical parameters when patient is able to ambulate full weight bearing without pain and on Xray images using RUSH score. Moreover Dexa scan will be performed pre-operatively and at 3 months postoperatively. The findings of this study will help in setting up guidelines for treatment of fragility proximal femur fractures in our population as there is still paucity of literature on effectiveness of strontium ranelate from our part of the world.

Conditions

• Fragility Fracture
• Femur; Fracture, Pertrochanteric
• Clinical Trial

Interventions

Type	Name	Description
DRUG	Strontium Ranelate	Dual mode of action, anabolic and anti-resorptive
DRUG	Lacto-N-Hexaose	Placebo look alike drug

Timeline

• Start date: 2021-11-01
• Primary completion: 2023-11-30
• Completion: 2024-06-30
• First posted: 2023-02-03
• Last updated: 2023-02-03

Locations

1 site across 1 country: Pakistan