NCT05711212

Effects of Xanthohumol on Resting Energy Expenditure and Substrate Oxidation in Healthy Women

Effects of Micellar Solubilized Xanthohumol on Resting Energy Expenditure and Substrate Oxidation in Healthy Women

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: University of Bonn · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to investigate the effects of Xanthohumol on resting energy expenditure and substrate oxidation in healthy women. It is assumed that resting energy expenditure and fatty acid oxidation is higher after Xanthohumol ingestion.

Detailed description

In a crossover design, 16 healthy young women ingest 172 mg micellar solubilized Xanthohumol or placebo in a randomized fashion. During an observational period of 3 hours, the acute effects of Xanthohumol on the resting energy expenditure and substrate oxidation is determined by respiratory gas analysis. An additional 30-minute determination of the resting energy expenditure and substrate oxidation is executed 24 hours after Xanthohumol ingestion. The wash-out period will be 28 days.

Conditions

• Resting Energy Expenditure

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	micellar solubilized Xanthohumol	single administration of 4 soft gelatine capsules each containing 43 mg micellar solubilized Xanthohumol
DIETARY_SUPPLEMENT	Placebo	single administration of 4 soft gelatine capsules containing only micelles

Timeline

• Start date: 2023-02-15
• Primary completion: 2024-04-30
• Completion: 2024-04-30
• First posted: 2023-02-02
• Last updated: 2024-05-28

Locations

1 site across 1 country: Germany