NCT05710068

Effects of RF Microneedle on Photoaging Skin

RF Microneedle Therapy Maintains the Treatment Effect of Melasma: A 32-week, Prospective, Randomized Split-face Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Ajou University School of Medicine · Academic / Other
• Sex: Female
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Melasma relapse is almost common after discontinuation of conventional treatment. Recent studies have suggested that photoaging dermis is main pathomechanism of melasma emphasizing stromal targeting therapy. Therefore, we investigated maintenance effect of microneedle radiofrequency (RF) for melasma treatment.

Conditions

• Pigmentation
• Pigmentation Disorder

Interventions

Type	Name	Description
DEVICE	RF Microneedle	Pulsed-type RF device in bipolar mode with 25 non-insulated microneedles every 2 weeks for 6 month
DRUG	Combination cream	5% hydroquinone, 0.003% tretinoin, and 1% hydrocortisone twice daily for 2 months

Timeline

• Start date: 2021-12-01
• Primary completion: 2022-08-01
• Completion: 2022-09-01
• First posted: 2023-02-02
• Last updated: 2023-02-02

Locations

1 site across 1 country: South Korea