NCT05706532

Cardiovascular and Cerebrovascular Control in Healthy Subjects

Cardiovascular and Cerebrovascular Control in Healthy Adult Subjects

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 60 (estimated)
• Sponsor: IRCCS Policlinico S. Donato · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to evaluate autonomic function and cerebrovascular control in 60 healthy subjects by means of noninvasive analysis of time series variability. To this extent, heart period, systolic and mean arterial blood pressure, cerebral blood velocity, peripheral resistances, respiration will be recorded from subjects during an orthostatic challenge. The interactions between autonomic cardiovascular function, cerebrovascular and peripheral control will be evaluated exploiting the most advanced signal processing techniques.

Conditions

• Healthy
• Autonomic Nervous System
• Cerebral Autoregulation

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	active standing	Data are acquired with patients resting in supine position for 10 minutes and for 10 minutes during active standing

Timeline

• Start date: 2023-05-29
• Primary completion: 2027-10-01
• Completion: 2027-10-01
• First posted: 2023-01-31
• Last updated: 2025-03-28

Locations

1 site across 1 country: Italy