NCT05704595

Effectiveness of Outpatient Intravenous Diuretic Therapy for Treatment of Worsening Heart Failure (OUTPATIENT-WHF)

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the OUTPATIENT-WHF study is to characterize the effectiveness of outpatient intravenous diuretic therapy as a treatment for worsening heart failure.

Detailed description

The purpose of this study is to determine whether treating certain patients with worsening heart failure as an outpatient with intravenous and oral medications can work just as well as treating patients in the hospital. Participants who enter into the study and meet eligibility criteria will be randomly chosen to either get intravenous diuretic like Lasix in the clinic and get outpatient care, versus directly admitted to the hospital to receive intravenous diuretic and normal hospital care.

Conditions

• Heart Failure

Interventions

Type	Name	Description
OTHER	Initial outpatient management strategy, including outpatient IV diuretics in clinic	Management strategy including IV diuretic in the outpatient clinic
OTHER	Initial hospitalization-based management strategy	Direct admission to the hospital

Timeline

• Start date: 2023-03-27
• Primary completion: 2025-04-01
• Completion: 2025-05-01
• First posted: 2023-01-30
• Last updated: 2025-04-27

Locations

1 site across 1 country: United States