Trials / Recruiting
RecruitingNCT05702398
Pilot Trial of Supplemental Vitamin A and Nicotinamide
Pilot Trial of Supplemental Vitamin A and Nicotinamide and Levels of Blood Vitamin A and Nicotinamide
- Status
- Recruiting
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- Sponsor
- Rhode Island Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this clinical trial is to assess the feasibility and safety of oral nicotinamide (NAM; a derivative of vitamin B3 \[niacin\]) and vitamin A in a high-risk population of kidney transplant recipients with a history of skin cancer to generate preliminary data for future cancer prevention clinical trials.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Vitamin A | 1,000 μg retinyl palmitate twice a day for 6 months |
| DRUG | Nicotinamide | 500 mg NAM twice a day for 6 months |
| OTHER | Other: Placebo | Identical placebo pills twice a day |
Timeline
- Start date
- 2023-04-01
- Primary completion
- 2028-01-01
- Completion
- 2028-03-01
- First posted
- 2023-01-27
- Last updated
- 2026-03-20
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05702398. Inclusion in this directory is not an endorsement.