NCT05701852

Motivational Behavioral and Functional MRI Impairment in Patients With Chronic Neuropathic Pain

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Fondation Ophtalmologique Adolphe de Rothschild · Network
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The main hypothesis of this study is that the alteration of the reward circuitry underlying the motivational deficit in chronic pain patients compared to healthy subjects results in a decrease in the capacity for reward learning. The fMRI studies have shown that this type of learning depends on the dopaminergic system innervating key regions of the reward system.

Conditions

• Chronic Pain

Interventions

Type	Name	Description
OTHER	reward learning task	during usual follow-up patients will complete a remard learning task questionnaire. This questionnaire cannot be assimilated to a clinical intervention.

Timeline

• Start date: 2023-12-19
• Primary completion: 2027-05-01
• Completion: 2027-05-01
• First posted: 2023-01-27
• Last updated: 2026-01-05

Locations

1 site across 1 country: France