NCT05699681

Correlation of Right Atrial Strain With Pulmonary Hypertension, Right Ventricular Function And Outcome In Pediatric Patients

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh · Academic / Other
• Sex: All
• Age: 1 Month – 12 Years
• Healthy volunteers: —

Summary

This observational study aims to assess correlation of right atrial strain measured by two-dimensional speckle tracking echocardiography with intraoperatively measured pulmonary artery pressures, other indices of right ventricular function and short term postoperative outcome.

Conditions

• Pulmonary Hypertension

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Transthoracic and transesophageal echocardiography	After induction of anaesthesia and stabilization of hemodynamics, transthoracic echocardiography will be done on a GE Vivid e9 workstation (GE Vingmed, Horton, Norway) with MS5 transthoracic probe with synchronized ECG. From TTE the following views and measurements will be acquired : * Apical four chamber (A4C) view * Apical two chamber view (A2C) view * Right ventricle (RV) focused A4C view * Right ventricular systolic pressure (RVSP) * Pulmonary arterial acceleration time (PAAT), * Tricuspid annular plane systolic excursion (TAPSE), * Tricuspid annular plane systolic velocity (s'), * Right ventricular fractional area change (RV FAC) * RV free wall strain, * RV myocardial performance index (MPI), * RV isovolumic relaxation time (IVRT), * RV isovolumic acceleration time (IVA) Invasive PA pressure measurement will be done after surgical exposure with a fine needle and a zeroed transducer by the Surgeon.

Timeline

• Start date: 2021-01-01
• Primary completion: 2023-01-31
• Completion: 2023-02-15
• First posted: 2023-01-26
• Last updated: 2023-01-26

Locations

1 site across 1 country: India