Trials / Completed
CompletedNCT05698849
Effect of Amino Acid Addition to a Drink on the Appearance of Ingested Water in Body Fluids (2859)
Effect of Amino Acid Addition to a Drink on the Appearance of Ingested Water in Body Fluids
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 15 (actual)
- Sponsor
- Loughborough University · Academic / Other
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
To determine the effects of a moderate amount of amino acids on the rate of water absorption and availability as a precursor fluid for sweat. Young and healthy (male or female) volunteers will take part in three experimental trials. In each trial, volunteers will be given one of two commercially available sports drinks or a commercially available sport drink with added amino acids in a double-blinded, randomised, crossover design. Each drink will be a single 550 mL bolus. All beverages will be labelled with deuterium (D2O). Trials will be compared for temporal accumulation of deuterium in plasma over the course of 60 minutes. Whole blood measurements of haemoglobin and haematocrit will also be made and plasma volume changes calculated. It is hypothesised that the amino acid trial will increase the rate of fluid absorption.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Composition of Sports Drink | The composition of sport drinks will be manipulated to determine the effect of drink composition on the appearance of ingested water in body fluid. |
Timeline
- Start date
- 2021-08-04
- Primary completion
- 2022-01-27
- Completion
- 2022-07-11
- First posted
- 2023-01-26
- Last updated
- 2025-02-07
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT05698849. Inclusion in this directory is not an endorsement.