NCT05698563

Intermetatarsal Bursitis in Patients With Rheumatoid Arthritis

Clinical Implication of Intermetatarsal Bursitis in Patients With Rheumatoid Arthritis

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: Rigshospitalet, Denmark · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to investigate the incidence and clinical implications of intermetatarsal bursitis (IMB) in patients with rheumatoid arthritis (RA). The hypothesis is that IMB is a cause of pain in patients with RA.

Detailed description

Within the recent years more research have focused on IMB in patients with rheumatologic disorders. There is emerging evidence that IMB is an inflammatory alteration in line with synovitis in patients with RA, and presence of IMB have been linked to the early stages of RA, especially due to the focus of the published literature. The clinical implications of the presence of IMB for the patients are yet to be understood. Limited studies have linked the occurrence of IMB to foot impairment, but no studies have been conducted investigating the direct association between forefoot pain and the presence/absence of IMB.

Conditions

• Intermetatarsal Bursitis
• Rheumatoid Arthritis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Magnetic resonance imaging	MRI scan with contrast of the foot or feet
DIAGNOSTIC_TEST	Ultrasound	Ultrasound scan of the feet
DRUG	Corticosteroid injection	Administered ultrasound guided to patients with intermetatarsal bursitis
OTHER	Clinical foot evaluation	An examination of the feet
OTHER	Picture of the feet	To evaluate the presence of V-sign/spreading toes

Timeline

• Start date: 2023-01-18
• Primary completion: 2023-02-14
• Completion: 2024-12-12
• First posted: 2023-01-26
• Last updated: 2025-09-22

Locations

1 site across 1 country: Denmark