Clinical Trials Directory

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UnknownNCT05698160

Biomarkers and Prediction of Tigecycline Induced Coagulation Dysfunction

Biomarkers and Prediction of Tigecycline Induced Coagulation Dysfunction Based on Multi-omics and Machine Learning Techbology

Status
Unknown
Phase
Study type
Observational
Enrollment
200 (estimated)
Sponsor
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is to screen out the biomarkers and establish the model to predict coagulation dysfunction induced tigecycline

Detailed description

The critically ill patients treated with tigecycline in in tensive care unit will be recruited and divided into tigecycline-induced coagulation dysfunction group and non-coagulation dysfunction group. The multi-omics will be used to screen out biomarkers for early prediction of coagulation dysfunction caused by tigecycline. Afterwards, machine learning methods will be adopted to establish the the early prediction model of tigecycline-induced coagulation dysfunction.

Conditions

Timeline

Start date
2023-05-01
Primary completion
2025-12-31
Completion
2025-12-31
First posted
2023-01-26
Last updated
2023-04-19

Source: ClinicalTrials.gov record NCT05698160. Inclusion in this directory is not an endorsement.