NCT05697471

Comparisons of the Therapeutic Effects of Dienogest and Danazol on Endometriosis

Far Eastern Memorial Hospital

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Far Eastern Memorial Hospital · Academic / Other
• Sex: Female
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to evaluate the efficacy between dienogest and danazol.

Detailed description

Objective: Women with adenomyosis or endometripsis are often suffered from dysmenorrhea or menorrhagia. Dienogest and danazol are frequently used for the treatment of endometriosis. However, there was no literature mentioned about which medication is better for the treatment of endometriosis. Thus, the aim of this study is to evaluate the efficacy between dienogest and danazol. Methods: All consecutive women, who have endometriosis, will be randomized to receive dienogest or danazol treatment, and will assess symptoms severity, receive CA125 examination, sonographic examination at baseline, 4 weeks and 16 weeks after treatment.

Conditions

• Endometriosis

Interventions

Type	Name	Description
DRUG	Dienogest	Dienogest 2 mg per day
DRUG	Danazol	Danzol 200MG per day

Timeline

• Start date: 2023-02-25
• Primary completion: 2025-12-31
• Completion: 2025-12-31
• First posted: 2023-01-26
• Last updated: 2023-03-29

Locations

1 site across 1 country: Taiwan