NCT05693064

The Impact of Chiropractic on Long COVID-19

The Impact of Chiropractic on Fatigue & the Autonomic Nervous System in Adults With Long COVID-19: a Waitlist-controlled, Single-blind, One-way Crossover, Pilot Trial

• Status: Suspended
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Life University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this waitlist-controlled, single-blind, one-way crossover, pilot trial is to evaluate the potential effects of \~8 weeks of chiropractic care on patient-reported fatigue and the autonomic nervous system in adults with long COVID. This study will allow us to estimate the standard deviation of the primary endpoint in our population with which a formal power calculation for a future randomized, controlled trial can be performed.

Detailed description

After providing informed consent, participants will be placed on an 8-week waitlist followed by 8 weeks of chiropractic care. In-person assessments will occur 5 times: Day 1, following 2-3 weeks on waitlist, following 8 weeks on waitlist, following 2-3 weeks of chiropractic care, and following 8 weeks of chiropractic care. Patient-reported outcomes will additionally be sent prior to the first in-person assessment (Day 0). Assessments will include the following: 1. Seated resting recording 2. Sit-to-stand test 3. Patient-reported outcome surveys Each assessment will consist of the following recordings: 1. Electroencephalography \[EEG\] 2. Impedance cardiography \[ICG\] 3. Electrocardiogram \[ECG\]

Conditions

• Long COVID

Interventions

Type	Name	Description
OTHER	wait-list	wait-list
PROCEDURE	chiropractic adjustments	chiropractic adjustments

Timeline

• Start date: 2025-01-15
• Primary completion: 2025-06-15
• Completion: 2025-08-01
• First posted: 2023-01-20
• Last updated: 2024-08-28

Locations

1 site across 1 country: United States