NCT05692037

Yttrium-90 Carbon Microspheres in Patients With Unresectable Colorectal Liver Metastases

Yttrium-90 Carbon Microspheres in Patients With Unresectable Colorectal Liver Metastases: A Multicentre, Prospective, Open-label, Single-arm Trial

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Zhongda Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the efficacy and safety of yttrium-90 carbon microspheres in patients with unresectable colorectal liver metastases

Detailed description

The efficacy and safety of yttrium-90 carbon microspheres in patients with unresectable colorectal liver metastases remain unknown. This multicentre, prospective, open-label, single-arm trial is designed to evaluate the safety and efficacy of yttrium-90 carbon microspheres in patients with unresectable colorectal liver metastases. The primary endpoints are the progression-free survival rates of liver target lesions. While the secondary endpoints include the safety, tumor control, and the distribution characteristics of yttrium-90 carbon microspheres.

Conditions

• Unresectable Colorectal Liver Metastases

Interventions

Type	Name	Description
COMBINATION_PRODUCT	Selective internal radiation therapy (SIRT) with yttrium-90 carbon microspheres	Yttrium-90 carbon microspheres SIRT

Timeline

• Start date: 2022-12-28
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2023-01-20
• Last updated: 2023-01-30

Locations

1 site across 1 country: China