NCT05691686

Bread Structure and Postprandial Metabolic Responses

Effects of Less-processed Whole Grain Bread Products (Wheat and Fortified With Legumes) on Postprandial Glucose and Subsequent Metabolic Responses.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Harokopio University · Academic / Other
• Sex: All
• Age: 20 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The structural properties of bread are considered one of the most important factors that can affect its digestibility, glucose homeostasis and postprandial metabolic responses. The purpose of this study is to examine the effects of consumption of less processed whole grain bread products (wheat and fortified with legumes) in comparison with finely milled whole grain bread products on postprandial glycaemic response and appetite regulation.

Detailed description

Postprandial glucose response caused by bread products of different degree of processing, as well as their appetite regulating properties will be evaluated. In the intervention there are totally four samples, the reference (white wheat bread), the less processed whole wheat bread, the whole wheat bread fortified with finely milled legumes (chickpeas), the whole wheat bread fortified with less processed legumes (chickpeas). The volunteers that will be enrolled in the study should be apparently healthy subjects (women and men) with normal body weight. Certain effects related to the structure of the different products on glycemic and insulinemic responses, subjective appetite ratings and other parameters will be examined.

Conditions

• Postprandial Hyperglycemia

Interventions

Type	Name	Description
OTHER	Finely milled whole wheat-legume bread	The intervention examines the effect of finely milled wheat-legume bread in subjects with normal body weight.
OTHER	Less processed whole wheat-legume bread	The intervention examines the effect of less processed whole wheat-legume bread in subjects with normal body weight.
OTHER	Less processed whole wheat bread	The intervention examines the effect of less processed whole wheat bread in subjects with normal body weight.
OTHER	White wheat bread	The intervention examines the reference food product in subjects with normal body weight.

Timeline

• Start date: 2023-01-16
• Primary completion: 2023-05-15
• Completion: 2023-10-31
• First posted: 2023-01-20
• Last updated: 2024-03-05

Locations

1 site across 1 country: Greece