Trials / Unknown
UnknownNCT05690542
Nanoparticles in Blood: Understanding and Controlling Protein Corona for Optimized Nanomedicine
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 60 (estimated)
- Sponsor
- Centre Hospitalier Universitaire Dijon · Academic / Other
- Sex
- All
- Age
- 18 Years – 79 Years
- Healthy volunteers
- —
Summary
The main objective is to study the effect of engineered nanoparticles SPIONs (superparamagnetic iron oxide) on hemostasis. Nanoparticles will be incubated in blood and platelet aggregation will be measured. In parallel, nanoparticles will also be incubated in blood and then plasma proteins adsorbed on them will be separated and analyzed. The proteins found on the nanoparticles will be linked to the platelet aggregation observed to help developing innovative protein functionalized nanoprobes for optimized nanomedicine.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | blood tests | evaluate the possible impact of iron oxide nanoparticles (superparamagnetic iron oxide = SPIONs) (N=10) in the blood circulation; |
Timeline
- Start date
- 2023-02-01
- Primary completion
- 2024-01-01
- Completion
- 2024-01-01
- First posted
- 2023-01-19
- Last updated
- 2023-01-19
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT05690542. Inclusion in this directory is not an endorsement.