NCT05690451

Non-contrast Abbreviated MRI for Secondary Surveillance of HCC

The Role of Non-contrast Abbreviated MRI for Secondary Surveillance of Hepatocellular Carcinoma After Curative Treatment: a Prospective Multicenter Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 210 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 85 Years
• Healthy volunteers: —

Summary

This prospective multicenter study aimed to compare the diagnostic performance of non-contrast abbreviated MRI in detecting recurrent HCC after curative treatment to that of contrast-enhanced liver CT.

Detailed description

This study was designed as a prospective single-arm intra-individual comparison multicenter study

Conditions

• Hepatocellular Carcinoma

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	non-contrast abbreviated MRI	Liver MRI without contrast injection. The following sequences will be obtained from all of the participants. * Axial heavily and regular T2 WI * precontrast fat-suppressed T1 WI * Diffusion-weighted image using b-value of 0, 50 or 400, and 800 or 1000
DIAGNOSTIC_TEST	Contrast enhanced liver CT	Liver CT with iodine contrast injection This test will be served as a standard diagnostic test. The following phases will be obtained * precontast, arterial phase, portal venous phase and delayed phase

Timeline

• Start date: 2021-12-28
• Primary completion: 2024-06-22
• Completion: 2024-06-22
• First posted: 2023-01-19
• Last updated: 2024-06-25

Locations

3 sites across 1 country: South Korea