NCT05688722

Head Elevation During Pre-oxygenation Can Delay Desaturation Time

Head Elevation During Pre-oxygenation Can Delay Desaturation Time in Indonesian Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 56 (actual)
• Sponsor: Indonesia University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study is a randomized-controlled trial study comparing the association between several degree of head elevation and conventional position during pre-oxygenation to desaturation time in patients undergo endotracheal intubation with general anesthesia

Detailed description

Preoxygenation anesthesia induction is an important part of airway management to reduce the risk of hypoxemia when the patient is apneic. The effectivity of preoxygenation is influenced by several things such as patient's head position. This study aimed to compare preoxygenation with head elevation 20°, 30° and 45° and conventional position to the time of desaturation before endotracheal intubation in patients undergoing general anesthesia. This was a randomized clinical trial of 56 patients, divided into four groups (conventional or 0° head elevation group, 20° head elevation group, 30° head elevation and 45° head elevation group). All subject was preoxygenated for 3 minutes with 100% oxygen. Induction of anesthesia was started with fentanyl, propofol, followed by rocuronium after the patient lost consciousness. Time was recorded from the start of induction until the oxygen saturation showed 93% or a time limit of 5 minutes. There was a significant difference in mean desaturation time among the four groups (p = 0.011). The most significant different was in 45o head elevation group (p \< 0.05). . In patients undergoing general anesthesia, pre-oxygenation with head elevation 20°, 30° and 45° slows down the time for desaturation before endotracheal intubation compared to the conventional position. The 45° head elevation has the best result.

Conditions

• Surgery
• Desaturation of Blood
• Apnea

Interventions

Type	Name	Description
PROCEDURE	Supine position	Patients preoxygenated in supine position before endotracheal intubation
PROCEDURE	20 degree head elevation position	Patients preoxygenated in 20 degree head elevation position before endotracheal intubation
PROCEDURE	30 degree head elevation position	Patients preoxygenated in 30 degree head elevation position before endotracheal intubation
PROCEDURE	45 degree head elevation position	Patients preoxygenated in 45 degree head elevation position before endotracheal intubation

Timeline

• Start date: 2021-04-01
• Primary completion: 2021-05-31
• Completion: 2021-05-31
• First posted: 2023-01-18
• Last updated: 2023-01-18

Locations

1 site across 1 country: Indonesia