Clinical Trials Directory

Trials / Completed

CompletedNCT05688670

Regional Anesthesia Following Pediatric Cardiac Surgery

Pain Control With Regional Anesthesia Following Pediatric Cardiac Surgery: A Randomized Double-Blinded Pilot Study

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
52 (actual)
Sponsor
Duke University · Academic / Other
Sex
All
Age
17 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to evaluate pain control following pediatric cardiac surgery with the use of local anesthesia via an ultrasound guided regional anesthetic technique compared with surgeon delivered wound infiltration.

Detailed description

This is a single center, randomized, double blind investigation which will compare postoperative pain control indices, functional recovery metrics and patient/parental satisfaction for pediatric patients receiving an ultrasound guided regional anesthetic versus surgeon delivered wound infiltration in children undergoing primary atrial and ventricular septal defect repairs. Surgical and anesthesia care, with the exception of the technique of local anesthetic administration, are not altered for study purposes. Subjects are randomized 1:1 to either bilateral Pecto-Intercostal Fascial Block and unilateral Rectus Sheath Block or infiltration of the wound through the perioperative period. Both interventions will use an equal volume of Ropivacaine 0.2% based on weight. Exploratory data will be collected for up to 30 days postoperatively.

Conditions

Interventions

TypeNameDescription
PROCEDURERegional AnesthesiaBilateral pecto-intercostal fascial plane block (PIFB) and unilateral rectus sheath block (RSB) with Ropivacaine 0.2%
PROCEDUREWound infiltrationSurgeon-delivered wound infiltration with Ropivacaine 0.2%
DRUGRopivacaine 0.2% Injectable SolutionRopivacaine 1.5 mL/kg will be used for both interventions

Timeline

Start date
2023-03-29
Primary completion
2024-10-18
Completion
2025-01-22
First posted
2023-01-18
Last updated
2025-08-28
Results posted
2025-08-28

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05688670. Inclusion in this directory is not an endorsement.