NCT05688111

Tranexamic Acid as an Intervention in Placenta Previa

Tranexamic Acid in Pregnant Women With Placentae Previa: A Double-blind, Multicenter Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 146 (actual)
• Sponsor: Hawler Medical University · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Antepartum hemorrhage (APH) due to placenta previa is an important cause of worldwide perinatal mortality and maternal morbidity in pregnant women

Detailed description

Antepartum hemorrhage (APH) due to placenta previa is an important cause of worldwide perinatal mortality and maternal morbidity in pregnant women. No medication is of specific benefit to a patient with placenta previa. Tocolysis may be cautiously considered in some circumstances in order to administer antenatal corticosteroids. A review article concluded that there is no improvement in perinatal outcome with prolonged tocolytics, and tocolysis beyond 48 hours is not clinically indicated.

Conditions

• Interventional Drug in Placenta Previa

Interventions

Type	Name	Description
DRUG	Tranexamic acid injection	Active group will receive 1gm Tranexamic acid 12 hourly for 48 hours
OTHER	Glucose water 5%	Placebo group 30ml will be received 12 hourly for 48 hours

Timeline

• Start date: 2022-12-10
• Primary completion: 2023-12-03
• Completion: 2023-12-03
• First posted: 2023-01-18
• Last updated: 2025-01-27

Locations

2 sites across 1 country: Iraq