NCT05687422

Two Patterns of Micropulse Laser in the Treatment of Chronic Central Serous Chorioretinopathy

A Randomized Controlled Study of Two Patterns of Micropulse Laser in the Treatment of Chronic Central Serous Chorioretinopathy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Beijing Hospital · Other Government
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Central serous chorioretinopathy (CSC) is a common eye disease mainly involving the macular area, causing central visual acuity loss. Recently, subthreshold micropulse laser used in treating chronic CSC is proved to be safe and effective. However, some studies indicate that it's less effective than half dose photodynamic therapy (PDT). Certain physicians, including us, think that this may be related to micropulse laser parameters. Thus we need to explore better laser patterns to replace PDT in treating chronic CSC. The aim of this study is to compare the treatment effect of two different patterns of laser parameters (small and regular spot diameter) in treating chronic CSC. In this randomized, double blinded, controlled trial, by comparing the subretinal fluid regression ratio, central retinal thickness, macular microvisual field, macular vascular density, chroidal volume changes and visual acuity of two groups 6 months after micropulse laser treatment, we aim to evaluate the safety and efficacy of refined micropulse laser in treating chronic CSC.

Conditions

• Central Serous Chorioretinopathy

Interventions

Type	Name	Description
PROCEDURE	100μm laser spot diameter micropulse laser	100μm laser spot diameter micropulse laser at baseline, then follow-up for 6 months
PROCEDURE	200μm laser spot diameter micropulse laser	200μm laser spot diameter micropulse laser at baseline, then follow-up for 6 months

Timeline

• Start date: 2023-02-01
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2023-01-18
• Last updated: 2023-01-18