Clinical Trials Directory

Trials / Terminated

TerminatedNCT05683678

US Selumetinib Registry

Status
Terminated
Phase
Study type
Observational
Enrollment
37 (actual)
Sponsor
Alexion Pharmaceuticals, Inc. · Industry
Sex
All
Age
2 Years – 18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to understand treatment patterns and assess long-term effectiveness and safety outcomes associated with selumetinib treatment as well as to explore clinical and non-clinical factors affecting those outcomes in patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PNs) who started selumetinib between the ages of 2 to 18 years inclusive, and initiated selumetinib treatment on or after 10 April 2020 in a real-world setting.

Detailed description

This is a US observational registry of pediatric NF1 PN participants treated with selumetinib.

Conditions

Timeline

Start date
2019-01-04
Primary completion
2024-11-13
Completion
2024-11-13
First posted
2023-01-13
Last updated
2025-04-04

Locations

10 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT05683678. Inclusion in this directory is not an endorsement.